What It Scores
ISSUE is a valid word in the tournament list this site uses. Tile values only, before any premium square: 5 in Scrabble and 6 in Words With Friends. The letters break down as I1 S1 S1 U1 E1.
Words Made From The Letters In ISSUE
15 shorter words come out of these tiles. On a board that matters more than the long play, because a short word on a premium square often beats a long one on plain squares.
4 letter words (4)
3 letter words (7)
2 letter words (4)
Longer Words Containing ISSUE
ISSUE appears inside each of these, which is what makes it worth knowing as a hook.
Next: the Word Unscrambler for any letters at all. Full entry and definition at Merriam-Webster.