What It Scores
PIOYE is a valid word in the tournament list this site uses. Tile values only, before any premium square: 10 in Scrabble and 11 in Words With Friends. The letters break down as P3 I1 O1 Y4 E1.
Words Made From The Letters In PIOYE
19 shorter words come out of these tiles. On a board that matters more than the long play, because a short word on a premium square often beats a long one on plain squares.
4 letter words (2)
3 letter words (7)
2 letter words (10)
Longer Words Containing PIOYE
PIOYE appears inside each of these, which is what makes it worth knowing as a hook.
Next: the Word Unscrambler for any letters at all. Full entry and definition at Merriam-Webster.