What It Scores
SIZIEST is a valid word in the tournament list this site uses. Tile values only, before any premium square: 16 in Scrabble and 16 in Words With Friends. The letters break down as S1 I1 Z10 I1 E1 S1 T1.
At seven letters this plays a whole rack, which is a bingo and worth 66 in Scrabble once the 50 point bonus lands.
Anagrams of SIZIEST (1)
Same letters, different order. Any of these plays the same tiles for the same score.
Words Made From The Letters In SIZIEST
43 shorter words come out of these tiles. On a board that matters more than the long play, because a short word on a premium square often beats a long one on plain squares.
6 letter words (1)
5 letter words (6)
4 letter words (16)
3 letter words (12)
2 letter words (8)
Next: the Word Unscrambler for any letters at all. Full entry and definition at Merriam-Webster.