What It Scores
SYZYGY is a valid word in the tournament list this site uses. Tile values only, before any premium square: 25 in Scrabble and 26 in Words With Friends. The letters break down as S1 Y4 Z10 Y4 G2 Y4.
Next: the Word Unscrambler for any letters at all. Full entry and definition at Merriam-Webster.